化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → Ave-9488
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 反応物 | 2-Aminoindan hydrochloride | HCID 122764 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Ave-9488 | HCID 10131276 | — |
反応手順
43.70 g (258 mol) 2-aminoindane hydrochloride and 53.43 g (528 mmol) triethylamine were added to 250 ml of tetrahydrofuran, 42.89 g (270 mmol) 4-fluorobenzoylchloride were added, and the mixture was stirred for 2 h at RT.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07179839B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-718b7980b122441ab1ee2810010504e8 |
| 出典メモ | uspto-grants-2007_02 |