Carbon Dioxide → Neopeltolide

HRID 349602

反応式

HRID 349602 の反応式
CCN([CH2:6][CH2:7][O:8][C:9]([C:11]1[CH:16]=[CH:15][C:14](N)=[CH:13][CH:12]=1)=[O:10])CC.CC1(C)S[C@@H]2[C@H](NC([CH2:30][C:31]3[CH:36]=C[CH:34]=[CH:33][CH:32]=3)=O)C(=O)N2[C@H]1C(O)=O.[OH2:41].[NH2:42][C@H:43](C(O)=O)[CH2:44][CH2:45][C:46](=[O:48])[NH2:47].C1N(C[CH2:59][OH:60])CCN(CCS(O)(=O)=O)C1.CC(NC)C1O[CH:73]([O:75][CH:76]2[CH:81](O)[CH:80]([O:83][CH:84]3[O:89]CC(O)(C)[CH:86](NC)[CH:85]3O)[CH:79](N)[CH2:78][CH:77]2N)C(N)CC1.[C:100](=O)=[O:101]>>[CH3:77][CH2:78][CH2:79][C@H:80]1[O:83][C:84](=[O:89])[CH2:85][C@@H:86]2[O:41][C@@H:33]([CH2:34][C@@H:7]([O:8][C:9](/[CH:11]=[CH:16]\[CH2:15][CH2:14][C:13]3[N:47]=[C:46](/[CH:45]=[CH:44]\[CH2:43][NH:42][C:100]([O:60][CH3:59])=[O:101])[O:48][CH:12]=3)=[O:10])[CH2:6]2)[CH2:32][C@@H:31]([CH3:30])[CH2:36][C@@H:76]([O:75][CH3:73])[CH2:81]1

参加物

6

反応物 5

HCID 280Carbon DioxideHCID 3467GentamicinHCID 5961L-GlutamineHCID 225024-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-(2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate, hydrate (1:1:1)HCID 238314-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

生成物 1

HCID 16115403Neopeltolide

実験手順

All cell lines are maintained in Roswell Park Memorial Institute (RPMI) medium 1640 supplemented with 100 U/mL penicillin 100 μg/ml streptomycin, 60 μg/ml L-glutamine, 18 mM HEPES, 0.05 mg/mL gentamycin and 10% fetal bovine serum. Cell lines are cultured in plastic tissue culture flasks and kept in an incubator at 37° C. in humidified air containing 5% CO2.

後処理

  1. temperatureAll cell lines are maintained in Roswell Park Memorial Institute (RPMI) medium 1640
  2. customCell lines are cultured in plastic tissue culture flasks
  3. customkept in an incubator at 37° C. in humidified air

出典と根拠

ORDレコード
ord-54430c6430da44529262d57f7ce4b87f
出典データセット
uspto-grants-2007_02
特許番号
US07179828B2

関連ノート

読み込み中…