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Hydrochloric Acid → (1-Chloropropyl)benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1-Phenyl-1-propanol | HCID 7147 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | (1-Chloropropyl)benzene | HCID 524241 | — |
反応手順
13.6 g (0.1 mole) of 1-phenylpropan-1-ol are taken up in petroleum ether and are reacted at -20° C. with hydrochloric acid until the precipitation of water is terminated. Subsequently, the organic phase is washed neutral with water, dried (sodium sulfate) and the petroleum ether removed in a vacuum. The bright yellow, thermolabile oil is used without further purification. The oil has an Rf of 0.8 (CH2Cl2) and is attained in a yield of 13.1 g (85%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04764533 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-dcd316a38b4f4ea7a34c064d42946357 |
| 出典メモ | uspto-grants-1988_08 |