化工社化工社 化学情報印刷レポート · 研究参考用
Dimethyl N-cyanodithioiminocarbonate → HCID 178503919、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl N-cyanodithioiminocarbonate | HCID 66289 | — |
| 反応物 | 3-{3-[(Pyrrolidin-1-yl)methyl]phenoxy}propan-1-amine | HCID 12797454 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | HCID 178503919 | HCID 178503919 | — |
反応手順
A solution of N-cyano-carbonimidodithioic acid dimethyl ester (5 g) in ethyl acetate (50 ml) was added to a solution of 3-[3-(1-pyrrolidinylmethyl)phenoxy]propanamine in ethyl acetate (60 ml). The reaction mixture was stirred at room temperature for 1 hr to give the title compound as an off-white solid m.p. 107°-108.5° (7.45 g). TLC silica; ethyl acetate: isopropanol:water:0.88 ammonia (25:15:8:2) single spot Rf 0.7.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04764612 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-8e99aae1d1e04736be34c3bafe85fee5 |
| 出典メモ | uspto-grants-1988_08 |