Potassium Carbonate → 4-((Allyl(methyl)amino)methyl)thiazol-2-amine

HRID 350959

反応式

HRID 350959 の反応式
[CH2:1]([NH:4][CH3:5])[CH:2]=[CH2:3].Cl.[NH2:7][C:8]1[S:9][CH:10]=[C:11]([CH2:13]Cl)[N:12]=1.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH2:1]([N:4]([CH2:13][C:11]1[N:12]=[C:8]([NH2:7])[S:9][CH:10]=1)[CH3:5])[CH:2]=[CH2:3]

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 69391N-MethylallylamineHCID 732282-Thiazolamine, 4-(chloromethyl)-, hydrochloride (1:1)

生成物 1

HCID 210906034-((Allyl(methyl)amino)methyl)thiazol-2-amine

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

N-allyl-N-methylamine (7.0 mg, 0.1 mmol), 2-amino-4-chloromethylthiazole hydrochloride (18.5 mg, 0.1 mmol), and potassium carbonate (30 mg, 0.21 mmol) are shaken in ethanol (1 mL) at room temperature for 18 hours. The mixture is filtered and the filtrate was condensed under vacuum.

後処理

  1. filtrationThe mixture is filtered
  2. customcondensed under vacuum

出典と根拠

ORDレコード
ord-6de76e9d87074e8c81db3041feaa73dd
出典データセット
uspto-grants-2007_02
特許番号
US07183300B2

関連ノート

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