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CP-671305 → (R)-N-[4-(1-Carbamoyl-ethoxy)-2-fluoro-benzyl]-2-(3-cyano-phenoxy)-nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | CP-671305 | HCID 9955578 | — |
| 反応物 | (R)-2-[3-Fluoro-4-({[2-(3-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid | HCID 60128037 | — |
| 生成物 | (R)-N-[4-(1-Carbamoyl-ethoxy)-2-fluoro-benzyl]-2-(3-cyano-phenoxy)-nicotinamide | HCID 10274542 | — |
反応手順
The compound of Formula (5.5.17) was prepared in a manner analogous to that described in Example 14, substituting (R)-2-[3-fluoro-4-({[2-(3-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid for the corresponding (R)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid material.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07183293B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-45b1100cbf11466dbac1a1cfdfb7df83 |
| 出典メモ | uspto-grants-2007_02 |