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1H-1,4-Benzodiazepine → 4-Chloro-6-(4-methyl-1-piperazinyl)-1,2,dihydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H-1,4-Benzodiazepine | HCID 148431 | — |
| 反応物 | N-[2-(5-chloro-1-indolinyl)phenyl]-4-methyl-1-piperazinecarboxamide | HCID 13823362 | — |
| 生成物 | 4-Chloro-6-(4-methyl-1-piperazinyl)-1,2,dihydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine | HCID 13823295 | — |
反応手順
It is predicted that if the N-[2-(5-chloro-2,3-dihydro-1H-indol- 1-yl)phenyl]-4-methyl-1-piperazinecarboxamide of Example 12a is treated in the manner of Example 4c that 6-(4-methyl-1-piperazinyl)-4-chloro-1,2-dihydrobenzo[b]3,2,1-jk][1,4]benzodiazepine will be obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04764616 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-78bef05da8164498bd433b7b1cd83d7b |
| 出典メモ | uspto-grants-1988_08 |