関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tributylvinyltin | HCID 81998 | — |
| 反応物 | 1-(Benzyloxy)-4-(1-iodoethenyl)benzene | HCID 18436326 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 1-(Benzyloxy)-4-(buta-1,3-dien-2-yl)benzene | HCID 18436327 | — |
反応手順
1-benzyloxy-4-(1-iodo-vinyl)-benzene (12.0 g, 0.035 mol), vinyl tributyl tin (16.0 mL, 0.056 mol) and PdCl2(CH3CN)2 (150 mg, 0.0579 mmol) were dissolved in DMF (300 mL). The reaction mixture was stirred at 25° C. for 16 h, then partitioned between ethyl acetate (800 mL) and H2O (400 mL). The organic layer was washed by brine, concentrated and purified on SiO2 (15% ethyl acetate/Hexane) to yield 1-benzyloxy-4-(1-methylene-allyl)-benzene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07183445B2 |
|---|
| 出典データセット | uspto-grants-2007_02 |
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| ORD ID | ord-54f9003c181d427dba66d593abb4a352 |
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| 出典メモ | uspto-grants-2007_02 |
|---|
