反応式
C[C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[C:8]([OH:11])[CH:7]=[CH:6][CH:5]=2.[C:12](=O)([O-])[O-].[K+].[K+].Br[CH2:19][C:20]([O:22][CH3:23])=[O:21].O>CN(C)C=O>[CH3:23][O:22][C:20](=[O:21])[CH:19]([O:11][C:8]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:9]=1[CH:10]=[CH:2][NH:3]2)[CH3:12]参加物
6
反応条件
- 温度
- 80 °C
実験手順
To a solution of 2-methyl-4-hydroxyindole (5 g) in N,N-dimethylformamide (50 ml) was added anhydrous potassium carbonate 11.7 g) and methyl bromoacetate (3.54 ml) at room temperature, and the mixture was stirred at 80° C. for 2 hours. To the reaction solution was added iced water to give the title compound (5.4 g) having the following physical data.
出典と根拠
- ORDレコード
- ord-ddab40e05b894d31ab8c82b4ed422700
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06743793B2
関連ノート
読み込み中…