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Hydrochloric Acid → 2-Methylindol-4-yloxyacetic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | 2-Methylindol-4-yloxyacetic Acid Methyl Ester | HCID 69130376 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-Methylindol-4-yloxyacetic Acid | HCID 69589397 | 69.2% |
反応手順
To a solution of 2-methylindol-4-yloxyacetic acid methyl ester (5.4 g) in methanol (18 ml)—dioxane (36 ml) was added 5N aqueous solution of sodium hydroxide (15 ml), and the mixture was stirred at room temperature for 1 hour. To the reaction solution was added 2N hydrochloric acid to give the title compound (3.5 g) having the following physical data.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06743793B2 |
| 出典データセット | uspto-grants-2004_06 |
| ORD ID | ord-e9bd21d5ed624234a0963aa400119c60 |
| 出典メモ | uspto-grants-2004_06 |