Methyl 2-(3-pyridylmethyl)naphthalene-6-carboxylate hydrochloride → 2-(3-Pyridylmethyl)naphthalene-6-carboxylic acid hydrochloride

HRID 35195ノート

反応式

HRID 35195 の反応式
[ClH:1].[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[C:14]([C:19]([O:21]C)=[O:20])[CH:15]=3)[CH:10]=2)[CH:3]=1>Cl>[ClH:1].[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[C:14]([C:19]([OH:21])=[O:20])[CH:15]=3)[CH:10]=2)[CH:3]=1

参加物

3

反応物 1

HCID 21295725Methyl 2-(3-pyridylmethyl)naphthalene-6-carboxylate hydrochloride

生成物 1

HCID 704078322-(3-Pyridylmethyl)naphthalene-6-carboxylic acid hydrochloride

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

A solution of 205 mg of methyl 2-(3-pyridylmethyl)naphthalene-6-carboxylate hydrochloride in 15 ml of 6N hydrochloric acid was refluxed for 18 hours. The solution was cooled to room temperature and the precipitate filtered off, washed with cold 6N hydrochloric acid followed by acetone and air dried to give 2-(3-pyridylmethyl)naphthalene-6-carboxylic acid hydrochloride, m.p. 265°-270° C.

後処理

  1. filtrationthe precipitate filtered off
  2. washwashed with cold 6N hydrochloric acid
  3. customdried

出典と根拠

ORDレコード
ord-c5f8d1cfcb224e08b8051b532a91ee86
出典データセット
uspto-grants-1988_08
特許番号
US04766127

反応ノート

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