化工社化工社 化学情報印刷レポート · 研究参考用
Taurine → 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-hydroxyphenoxy)-6-(2-hydroxysulfonylethylamino)pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Taurine | HCID 1123 | — |
| 反応物 | 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-methoxyphenoxy)-6-methoxycarbonylmethylamino-pyridine | HCID 9888184 | — |
| 生成物 | 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-hydroxyphenoxy)-6-(2-hydroxysulfonylethylamino)pyridine | HCID 22712113 | — |
反応手順
By use of 2-aminoethylsulfonic acid in place of glycine methyl ester for the preparation of Compound 1e followed by deprotection as described for example 2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06747048B2 |
| 出典データセット | uspto-grants-2004_06 |
| ORD ID | ord-0c10dec69a284944882e38c2d9a60f2f |
| 出典メモ | uspto-grants-2004_06 |