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HRID 352756作成日：2026年10月26日

4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester → 1-[4-(N-tert-butoxycarbonylpiperidin-4-yl)benzoyl]-4-(6-chloronaphthalene-2-sulfonyl)piperazine

https://huagongshe.com/reaction/352756

反応式

関与物質

役割名称HCID仕込み量
反応物4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 22492859—
反応物1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochlorideHCID 22709766—
生成物1-[4-(N-tert-butoxycarbonylpiperidin-4-yl)benzoyl]-4-(6-chloronaphthalene-2-sulfonyl)piperazineHCID 22710684—

反応手順

In the same manner as in Referential Example 12, a reaction was conducted using 4-(1-tert-butoxycarbonylpiperidin-4-yl)benzoic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as starting materials, whereby the title compound was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06747023B1
出典データセットuspto-grants-2004_06
ORD IDord-3edeb1d4a84a45a48204dca54ef09f79
出典メモuspto-grants-2004_06