Tert-butyl 4-benzylpiperazine-1-carboxylate → 1-Benzylpiperazine hydrochloride

HRID 352777

反応式

HRID 352777 の反応式
[CH2:1]([N:8]1[CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:21].C(O)C>>[ClH:21].[CH2:1]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 584330Tert-butyl 4-benzylpiperazine-1-carboxylateHCID 21887872Ethanol hydrochloride

生成物 1

HCID 27566531-Benzylpiperazine hydrochloride収率 97%

実験手順

To 1-benzyl-4-tert-butoxycarbonylpiperazine (3.12 g), saturated ethanol hydrochloride was added, followed by stirring for 90 minutes at room temperature. The solvent was distilled off under reduced pressure, followed by drying, whereby the title compound (2.73 g, 97%) was obtained as white powder.

後処理

  1. distillationThe solvent was distilled off under reduced pressure
  2. customby drying

出典と根拠

ORDレコード
ord-33705c0319e7456583203d04feae1405
出典データセット
uspto-grants-2004_06
特許番号
US06747023B1

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