Carbon Dioxide → HCID 23688411、化合物

HRID 352891ノート

反応式

HRID 352891 の反応式
[N:1]1[C:5]2[CH2:6][CH2:7][O:8][CH2:9][C:4]=2[S:3][CH:2]=1.C([Li:14])CCC.[C:15](=[O:17])=[O:16]>CCOCC>[N:1]1[C:5]2[CH2:6][CH2:7][O:8][CH2:9][C:4]=2[S:3][C:2]=1[C:15]([O-:17])=[O:16].[Li+:14]

参加物

5

反応物 3

HCID 280Carbon DioxideHCID 227102096,7-dihydro-4H-pyrano[4,3-d]thiazoleHCID 178418339Butyllithium

生成物 1

HCID 23688411HCID 23688411、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

反応条件

温度
-78 °C

実験手順

In a 200-mL three-necked flask, 4,5-dihydro-7H-pyrano[4,3-d]thiazole (1.14 g) was added and dissolved in ether (30 mL). After cooling to −78° C., 1.6M butyl lithium (6.6 mL) was added and the resulting mixture was stirred. After 20 minutes, a carbon dioxide gas was introduced. After about 15 minutes, the introduction was terminated. The reaction mixture was allowed to rise back to room temperature and concentrated under reduced pressure, whereby the title compound (1.65 g) was obtained as a colorless amorphous substance.

後処理

  1. waitAfter about 15 minutes
  2. customthe introduction was terminated
  3. customto rise back to room temperature
  4. concentrationconcentrated under reduced pressure, whereby the title compound (1.65 g)
  5. customwas obtained as a colorless amorphous substance

出典と根拠

ORDレコード
ord-fcb15ea9db4749e5a26354b3dc22d89a
出典データセット
uspto-grants-2004_06
特許番号
US06747023B1

反応ノート

読み込み中…