化工社化工社 化学情報印刷レポート · 研究参考用
Ethanolamine → N-(2-Hydroxyethyl)pyrazine-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanolamine | HCID 700 | — |
| 反応物 | Methyl pyrazinoate | HCID 72662 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | N-(2-Hydroxyethyl)pyrazine-2-carboxamide | HCID 14230272 | 80% |
反応手順
A mixture of 55.2 parts of methyl 2-pyrazinecarboxylate, 48.9 parts of 2-aminoethanol and 360 parts of ethyl acetate was allowed to stand overnight at room temperature. The precipitated product was filtered off, washed with ethyl acetate and dried, yielding 54.5 parts (80%) of N-(2-hydroxyethyl)-2-pyrazinecarboxamide; mp. 125° C. (intermediate 22).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04766125 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-5c89f624e3c24f21936bf0d2ca764d41 |
| 出典メモ | uspto-grants-1988_08 |