2-Acetylfuran → HCID 535936、化合物

反応式

[C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)(=[O:3])[CH3:2].CO[CH:11](OC)[N:12]([CH3:14])[CH3:13]>>[CH3:11][N:12]([CH3:14])[CH:13]=[CH:2][C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)=[O:3]

参加物

反応物 2

HCID 145052-Acetylfuran

HCID 78373Dimethylformamide dimethyl acetal

生成物 1

HCID 535936HCID 535936、化合物収率 97%

反応条件

温度: 100 °C

実験手順

A mixture of 2-acetylfuran (25.0 g, 0.227 mmol) and N,N-dimethylformamide dimethylacetal (40 ml) was stirred at 100° C. for 9 hours. After cooling as it was, the reaction solution was concentrated. Diethyl ether and hexane were added to the residue, and the resulting solid was collected by filtration and washed with hexane, to give the title compound (36.5 g, 97%) as a brown solid.

後処理

temperatureAfter cooling as it
concentrationthe reaction solution was concentrated
additionDiethyl ether and hexane were added to the residue
filtrationthe resulting solid was collected by filtration
washwashed with hexane

出典と根拠

ORDレコード: ord-f94a5246ce3443b092460200d15c6f49
出典データセット: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06750232B2

反応ノート

読み込み中…

参加物