化工社化工社 化学情報印刷レポート · 研究参考用
Calcium hypochlorite → HCID 22708344、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Calcium hypochlorite | HCID 24504 | — |
| 反応物 | HCID 22708350 | HCID 22708350 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 溶媒 | Acetic acid--water (1/1) | HCID 21899381 | — |
| 生成物 | HCID 22708344 | HCID 22708344 | 87% |
反応手順
To a solution of calcium hypochlorite (15.4 g, 72.4 mmol) in water:acetic acid (65:5) was added a solution of 8-trifluoromethoxychroman-4-one (4.2 g, 18.1 mmol; from step (iv) above) in acetonitrile (20 mL), whereafter the reaction mixture was stirred overnight. The mixture was diluted with water and extracted with ether (3 times) and EtOAc (once). The combined organic layer was washed with water, dried (Na2SO4) and evaporated, yielding 4.2 g (87%) of the sub-tide compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06750243B1 |
| 出典データセット | uspto-grants-2004_06 |
| ORD ID | ord-043020b1396d4c3b960816fe83620a9d |
| 出典メモ | uspto-grants-2004_06 |