Ammonia → Methyl 6-aminohexanoate

HRID 35382

反応式

HRID 35382 の反応式
[CH:1]([CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9][CH3:10])=[O:8])=[O:2].[NH3:11].[H][H]>>[NH2:11][CH2:1][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9][CH3:10])=[O:8].[C:1]1(=[O:2])[NH:11][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

参加物

5

反応物 3

HCID 222AmmoniaHCID 81164Methyl 6-oxohexanoateHCID 178418361HCID 178418361、化合物

生成物 2

HCID 7768Caprolactam収率 3.3%HCID 1810164Methyl 6-aminohexanoate収率 90%

実験手順

Thereafter, 2,200 g/hour of 9.86% strength by weight methanolic methyl 5-formylvalerate solution and 800 ml/hour (488 g/hour) of liquid ammonia were pumped through the reactor from below, while hydrogen was passed through simultaneously, at 80° C. and under 102 bar. The reaction mixture passed from the top of the reactor via a condenser into a separator, from which 2,596 g/hour of product mixture (regulated via the level control) and 207 l/hour of waste gas were removed. According to quantitative gas chromatographic analysis, the discharge of the mixture contained 7.57% of methyl 6-aminocaproate and 0.22% of caprolactam, corresponding to yields of 90.0% of methyl 6-aminocaproate and 3.3% of caprolactam, percentages being based on the completely converted methyl 5-formylvalerate.

後処理

  1. customat 80° C.
  2. customThe reaction mixture passed from the top of the reactor via a condenser into a separator, from which 2,596 g/hour of product mixture
  3. customwere removed

出典と根拠

ORDレコード
ord-aa0772dc4d5d4765804b9b7f1513b789
出典データセット
uspto-grants-1988_08
特許番号
US04766237

関連ノート

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