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Hypofluorous acid, trifluoromethyl ester → Methanesulfonamide, N-phenyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hypofluorous acid, trifluoromethyl ester | HCID 78989 | — |
| 反応物 | Bis(fluoroxy)perfluoromethane | HCID 140054 | — |
| 反応物 | N-(2-Fluorophenyl)methanesulfonamide | HCID 669015 | — |
| 反応物 | N-(2,4-difluorophenyl)methanesulfonamide | HCID 669157 | — |
| 反応物 | N-(4-fluorophenyl)methanesulfonamide | HCID 773417 | — |
| 反応物 | N-(2,6-difluorophenyl)methanesulfonamide | HCID 13498497 | — |
| 生成物 | Methanesulfonamide, N-phenyl- | HCID 70970 | — |
反応手順
The procedure of Example 26 was repeated except that in place of the fluoroxytrifluoromethane, there was added bis-(fluoroxy)difluoromethane at a rate of 2.40 parts per hour for one hour. Analysis of the reaction product by liquid chromatographic techniques indicated 38% N-(2-fluorophenyl)methanesulfonamide, 12% N-(4-fluorophenyl)methanesulfonamide, 10% N-(2,4-difluorophenyl)methanesulfonamide and 1% N-(2,6-difluorophenyl)methanesulfonamide at 97% conversion.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04766243 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-760c8144346a4e968d0ba51e241675e6 |
| 出典メモ | uspto-grants-1988_08 |