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N-Methylol-alpha-chloroacetamide → 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-Methylol-alpha-chloroacetamide | HCID 62466 | — |
| 反応物 | 4-(1,1-Dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol | HCID 54155563 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide | HCID 53948117 | — |
反応手順
3 g (0.01 mole) of 4-(1,1-dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol are dissolved in 30 ml of sulfuric acid, and 1.1 g (0.009 mole) of 2-chloro-N-hydroxymethylacetamide are added. The mixture is stirred for 30 minutes at room temperature and poured into ice water. The product is filtered off with suction and recrystallized from methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04766241 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-aef4cd9e4021414984007a97f385e38f |
| 出典メモ | uspto-grants-1988_08 |