N-Methylol-alpha-chloroacetamide → 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide

HRID 35397

反応式

[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[C:7]([S:12]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])(=[O:14])=[O:13])[CH:6]=1)([CH3:4])[CH3:3].[Cl:20][CH2:21][C:22]([NH:24][CH2:25]O)=[O:23]>S(=O)(=O)(O)O>[Cl:20][CH2:21][C:22]([NH:24][CH2:25][C:9]1[CH:10]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[CH:6]=[C:7]([S:12]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])(=[O:13])=[O:14])[C:8]=1[OH:11])=[O:23]

参加物

実験手順

3 g (0.01 mole) of 4-(1,1-dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol are dissolved in 30 ml of sulfuric acid, and 1.1 g (0.009 mole) of 2-chloro-N-hydroxymethylacetamide are added. The mixture is stirred for 30 minutes at room temperature and poured into ice water. The product is filtered off with suction and recrystallized from methanol.

後処理

filtrationThe product is filtered off with suction
customrecrystallized from methanol

出典と根拠

ORDレコード: ord-aef4cd9e4021414984007a97f385e38f
出典データセット: uspto-grants-1988_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04766241

反応式

参加物

反応物 2

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

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