Selenium Dioxide → 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

HRID 354035ノート

反応式

HRID 354035 の反応式
[CH3:1][C:2]1[O:3][C:4](=[O:8])[O:5][C:6]=1[CH3:7].[Se](=O)=[O:10]>O1CCOCC1>[CH3:7][C:6]1[O:5][C:4](=[O:8])[O:3][C:2]=1[CH2:1][OH:10]

参加物

4

反応物 2

HCID 24007Selenium DioxideHCID 1422104,5-Dimethyl-1,3-dioxol-2-one

生成物 1

HCID 105108784-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

A solution of 4,5-dimethyl-2-oxo-1,3-dioxolene (1 mmole) and selenium dioxide (2.5 mmole) in dioxane was heated at reflux for 1 h. Evaporation, extraction and chromatography gave 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene as a yellow oil. TLC: RPf=0.5, 5% MeOH-dichloromethane.

後処理

  1. temperatureat reflux for 1 h
  2. customEvaporation, extraction and chromatography

出典と根拠

ORDレコード
ord-00ab9a8fb71941918916069b9a5c11f7
出典データセット
uspto-grants-2004_06
特許番号
US06756360B1

反応ノート

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