1-Ethyl-3-methylimidazolium chloride → n-Carboxymethyl-3,4,5,6-tetrahydroaniline

92 mg (0.5 mmol) of N-carboxymethyl-3-amino-1,7-octadiene and 4 mg of bis(tricyclohexylphosphine)-benzylidene-ruthenium(IV) dichloride (1 mol %) were dissolved in a liquid mixture of 586 mg of 1-methyl-3-ethylimidazolium chloride (4 mmol) and 533 mg of aluminium trichloride (4 mmol) under an argon atmosphere in a baked-out Schlenk tube. The mixture was allowed to react for two hours at 50° C. After an aqueous work-up, the mixture was filtered through a very short silica gel column (0.5 cm), washed four times with 1 ml each time of acetonitrile and evaporated.

1. customto react for two hours at 50° C
2. filtrationAfter an aqueous work-up, the mixture was filtered through a very short silica gel column (0.5 cm)
3. washwashed four times with 1 ml each time of acetonitrile
4. customevaporated

ORDレコード

ord-d51f72ceb9fa4e588f4c3170ac7be1b1

出典データセット

uspto-grants-2004_06

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US06756500B1