Water → Benzenebutanenitrile
反応式
Br[CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[C-]#[N:13].[Na+].O>C(O)C>[C:6]1([CH2:5][CH2:4][CH2:3][C:2]#[N:13])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1参加物
5
実験手順
A mixture of 1-bromo-4-phenylbutane (58.8 g, 0.24 mole) and sodium cyanide (25 g, 0.5 mole) in ethanol (300 ml)-water (100 ml) is heated at reflux with stirring for 5 hours. The resulting reaction mixture is concentrated in vacuo and extracted with ether. The ethereal extract is filtered and evaporated at reduced pressure to afford the title compound which is purified by distillation.
後処理
- temperatureis heated
- temperatureat reflux
- customThe resulting reaction mixture
- concentrationis concentrated in vacuo
- extractionextracted with ether
- extractionThe ethereal extract
- filtrationis filtered
- customevaporated at reduced pressure
出典と根拠
- ORDレコード
- ord-4452a13b4caa4deea43bee9374ff835c
- 出典データセット
- uspto-grants-1983_03
- 特許番号
- US04375475
反応ノート
読み込み中…