1,4-Dibromo-2-butyne → 1-(4-Bromo-2-butyn-1-yl)-5, 6-dichloro-3-ethyl-2-methylbenzimidazolium bromide

HRID 354592

反応式

HRID 354592 の反応式
[Cl:1][C:2]1[C:13]([Cl:14])=[CH:12][C:5]2[N:6]([CH2:10][CH3:11])[C:7]([CH3:9])=[N:8][C:4]=2[CH:3]=1.[Br:15][CH2:16][C:17]#[C:18][CH2:19]Br>CCOCC>[Br-:15].[Br:15][CH2:16][C:17]#[C:18][CH2:19][N+:8]1[C:4]2[CH:3]=[C:2]([Cl:1])[C:13]([Cl:14])=[CH:12][C:5]=2[N:6]([CH2:10][CH3:11])[C:7]=1[CH3:9]

参加物

4

反応物 2

HCID 752051,4-Dibromo-2-butyneHCID 767171H-Benzimidazole, 5,6-dichloro-1-ethyl-2-methyl-

生成物 1

HCID 867388101-(4-Bromo-2-butyn-1-yl)-5, 6-dichloro-3-ethyl-2-methylbenzimidazolium bromide

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

5,6-Dichloro-1-ethyl-2-methylbenzimidazole (11.5 g., 0.05 moles) and 1,4-dibromo-2-butyne (31 g., 0.15 moles) were mixed together and stirred at room temperature overnight. The reaction mixture was treated with ether, the solid was collected by filtration, washed with ether and dried. It was recrystallized from acetonitrile containing 5% water (400 ml). The product was recovered in two crops. Yield 20.2 g (92%), mp. 185°-189° C.

後処理

  1. filtrationthe solid was collected by filtration
  2. washwashed with ether
  3. customdried
  4. customIt was recrystallized from acetonitrile containing 5% water (400 ml)
  5. customThe product was recovered in two crops

出典と根拠

ORDレコード
ord-2a5f7d380d3e4f4693277dabeadcca5f
出典データセット
uspto-grants-1983_03
特許番号
US04375508

関連ノート

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