Chrysanthemic Acid → alpha-Fluoro-3-phenoxybenzyl 3-(2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

HRID 354708

反応式

HRID 354708 の反応式
[CH3:1][C:2]([CH3:12])=[CH:3][CH:4]1[CH:6]([C:7]([OH:9])=[O:8])[C:5]1([CH3:11])[CH3:10].[F:13][CH:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:16]=1>>[CH3:1][C:2]([CH3:12])=[CH:3][CH:4]1[CH:6]([C:7]([O:9][CH:14]([F:13])[C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:16]=2)=[O:8])[C:5]1([CH3:11])[CH3:10]

参加物

3

反応物 2

HCID 2743Chrysanthemic AcidHCID 13194583alpha-Fluoro-3-phenoxybenzylbromide

生成物 1

HCID 12855309alpha-Fluoro-3-phenoxybenzyl 3-(2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

実験手順

This compound was prepared from 3-(2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and α-fluoro-3-phenoxybenzylbromide following the procedure described in Example 2 Method B. The product, a colourless oil, was characterised by pmr spectroscopy. Chemical shift δppm (solvent CDCl3): 1.24 (6H, m, C(CH3)2); 1.70 (6H, s, (CH3)2C=); about 1.9 (2H, m, cyclopropyl protons); 4.93 and 5.43 (1H, 2xd, J=7 Hz, vinyl proton); 7.13 (1H, d, J=56 Hz, CHF); about 7.1 (9H, m, aromatic protons).

出典と根拠

ORDレコード
ord-16e3154840c54784bf62fdeb5aec0a91
出典データセット
uspto-grants-1983_03
特許番号
US04376784

関連ノート

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