Acetic Acid → HCID 13060513、化合物
反応式
[NH2:1][C:2]1[CH:9]=[C:8](CC)[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[O-:12][C:13]#[N:14].[K+].[C:16](O)(=O)[CH3:17]>O>[C:4]([C:3]1[CH:6]=[C:7]([CH2:16][CH3:17])[CH:8]=[CH:9][C:2]=1[NH:1][C:13]([NH2:14])=[O:12])#[N:5]参加物
5
実験手順
To a solution of 2-amino-4-ethylbenzonitrile (39.9 g) in acetic acid (200 ml) was added potassium cyanate (24.4 g) under ice-cooling in the course of 15 minutes and stirred overnight in water bath. To the resultant mixture was added water to give precipitates, which were separated by filtration, washed with water and dried at ambient temperature. The resultant crude crystals were recrystallized from ethanol to give crystalline (2-cyano-4-ethylphenyl)urea (29.0 g).
後処理
- temperaturecooling in the course of 15 minutes
- customto give
- customprecipitates
- customwhich were separated by filtration
- washwashed with water
- customdried at ambient temperature
- customThe resultant crude crystals were recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-588611f1aff541a68cac883c29b0db67
- 出典データセット
- uspto-grants-1983_03
- 特許番号
- US04377580
反応ノート
読み込み中…