関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Ethyl 4-hydroxypiperidine-1-carboxylate | HCID 96394 | — |
| 反応物 | Bromodiphenylmethane | HCID 236603 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl 4-(diphenylmethoxy)piperidine carboxylate | HCID 10020094 | — |
反応手順
A mixture of 17.3 parts of 1-(ethoxycarbonyl)-4-hydroxypiperidine, 24.7 parts of bromodiphenylmethane and 7 parts of potassium carbonate is stirred and heated in an oil-bath for 3 hours at 140° C. The reaction mixture is cooled, water is added and the product is extracted with methylbenzene. The extract is washed a few times with water, dried, filtered and evaporated. The oily residue is distilled, yielding ethyl 4-(diphenylmethoxy)-1-piperidinecarboxylate; bp. 150° C. at 0.4 mm. pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04377578 |
|---|
| 出典データセット | uspto-grants-1983_03 |
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| ORD ID | ord-276822bab8634971bcbaf70aa53751a4 |
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| 出典メモ | uspto-grants-1983_03 |
|---|
