化工社化工社 化学情報印刷レポート · 研究参考用
Isobutyric Acid → 5-Chloro-2,3-dimethylpentanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isobutyric Acid | HCID 6590 | — |
| 反応物 | 1,3-Dichloropropane | HCID 8881 | — |
| 反応物 | 6-Bromo-2,3-dimethylhexanoic acid | HCID 18942136 | — |
| 生成物 | 5-Chloro-2,3-dimethylpentanoic acid | HCID 18942134 | — |
反応手順
The title compound was prepared as described for 6-bromo-2,3-dimethylhexanoic acid from isobutyric acid (9.67 g, 109.8 mmol), and 1,3-dichloropropane (37.2 g, 329.2 mmol). The product was purified by flash chromatography (CHCl3) to provide the acid (0.9 g, 5%) as a oil, HRMS (M+Li)+ calcd for C7H13O2ClLi 171.0764, found 171.0766.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05830888 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-9dc23f2b8639435eb4cb47e15da30ebc |
| 出典メモ | uspto-grants-1998_11 |