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HRID 356284作成日:2026年10月25日

Methyl (4-nitrophenoxy)acetate → Methyl(4-aminophenoxy)acetate

https://huagongshe.com/reaction/356284

反応式

関与物質

役割名称HCID仕込み量
反応物Methyl (4-nitrophenoxy)acetateHCID 700522—
触媒PalladiumHCID 23938—
溶媒MethanolHCID 887—
生成物Methyl(4-aminophenoxy)acetateHCID 642211597.6%

反応手順

A procedure similar to that described in Example 6 was repeated, except that 30.8 g of methyl 4-nitro-phenoxyacetate (prepared as described in Preparation 36), 5.0 g of 10% w/w palladium-on-charcoal and 500 ml of methanol were used, to give 25.8 g of the title compound having Rf=0.79 (on silica gel thin layer chromatography using ethyl acetate as the developing solvent).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05834501
出典データセットuspto-grants-1998_11
ORD IDord-d75c053e7dda43a784c033be9ddf82c9
出典メモuspto-grants-1998_11