化工社化工社 化学情報印刷レポート · 研究参考用
Cyclohexyl methyl ketone → 3-(4-Benzyloxy-phenyl)-1-cyclohexyl-prop-2-en-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexyl methyl ketone | HCID 13207 | — |
| 反応物 | Benzaldehyde, 4-(phenylmethoxy)- | HCID 78109 | — |
| 反応物 | Barium hydroxide | HCID 6093286 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-(4-Benzyloxy-phenyl)-1-cyclohexyl-prop-2-en-1-one | HCID 471477 | — |
反応手順
The title compound was prepared as described in General Method 2 using 17.40 g (138 mmol) of cyclohexyl methyl ketone, 29.26 g (138 mmol) of 4-benzyloxybenzaldehyde, 3.17 g of barium hydroxide (anhydrous), and 300 mL of 95% EtOH. The reaction was heated at reflux for eight hours. The crude product was recrystallized from EtOAc. The 25.85 g of product, contaminated with some 4-benzyloxybenzaldehyde, was taken on without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05834506 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-8e577549f35c46388dfd37bc0e3e764c |
| 出典メモ | uspto-grants-1998_11 |