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Imidazole → 4-(4-tert-Butyldimethylsilyloxy-phenyl)-2-butanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | 4-(4'-Hydroxyphenyl)-2-butanone | HCID 21648 | — |
| 反応物 | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-(4-tert-Butyldimethylsilyloxy-phenyl)-2-butanone | HCID 18798666 | — |
反応手順
The title compound was prepared as described in General Method 5 using 10 g (60.9 mmol) of 4-(4-hydroxyphenyl)-2-butanone, 10.1 g (67 mmol) of tert-butyldimethyl silyl chloride, 4.56 g (67 mmol) of imidazole and 150 mL of DMF. The crude product was carried on "as is" to the next step (see Example KK).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05834506 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-ffc34ceb05ed44a58e42ad7c9732bf74 |
| 出典メモ | uspto-grants-1998_11 |