Hydrochloric Acid → HCID 18939138、化合物

HRID 356688

反応式

HRID 356688 の反応式
Cl[C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5](=[O:16])[C:4]=2[CH:3]=1.[K].[SH:18][CH2:19][CH2:20][OH:21].CN(C)C(=O)C.Cl>>[OH:21][CH2:20][CH2:19][S:18][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5](=[O:16])[C:4]=2[CH:3]=1

参加物

6

反応物 5

HCID 313Hydrochloric AcidHCID 15672-MercaptoethanolHCID 31374DimethylacetamideHCID 6188482-ChlorothioxanthoneHCID 5462222Potassium

生成物 1

HCID 18939138HCID 18939138、化合物

実験手順

5.6 g (0.0225 mol) of 2-chlorothioxanthone and 2.6 g (0.0225 mol) of the potassium salt of 2-mercaptoethanol are stirred for 18 hours in 20 mol of N,N-dimethylacetamide at 100° C. The reaction mixture is then poured into 2N hydro-chloric acid and extracted with ethyl acetate. After conventional work-up and chromatographic purification, 3.5 g of the analytically pure compound IIIa of melting point 94° C. are obtained.

後処理

  1. extractionextracted with ethyl acetate
  2. customAfter conventional work-up and chromatographic purification, 3.5 g of the analytically pure compound IIIa of melting point 94° C.
  3. customare obtained

出典と根拠

ORDレコード
ord-d2dbb9a41f3b4454a5508942d0219ba3
出典データセット
uspto-grants-1998_11
特許番号
US05837746

関連ノート

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