化工社化工社 化学情報印刷レポート · 研究参考用
Water → 3-Isopropoxy-4-methoxybenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Bromopropane | HCID 6358 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Isovanillin | HCID 12127 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-Isopropoxy-4-methoxybenzaldehyde | HCID 592092 | — |
反応手順
A mixture of 3-hydroxy-4-methoxybenzaldehyde (20.0 g), anhydrous potassium carbonate (26.2 g) and 2-bromopropane (18.3 mL) in dry dimethylformamide (300 mL) is stirred and heated at 55°-65° C. for 24 hours. The cooled mixture is poured into water and extracted with ethyl acetate. The extract is dried over magnesium sulfate and concentrated in vacuo at 40° C., to give 4-methoxy-3-prop-2-yloxybenzaldehyde, in the form of an oil (24.2 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05840724 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-9eb09239ec3e490088c7d9619b869569 |
| 出典メモ | uspto-grants-1998_11 |