Hydrochloric Acid → 5-Decylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride
反応式
[CH:1](=[C:11]1[S:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][S:21][C:22]2[N:27]3[CH:28]=[CH:29][N:30]=[C:26]3[CH:25]=[CH:24][CH:23]=2)[C:12]1=[O:31])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[ClH:32]>CO>[ClH:32].[CH:1](=[C:11]1[S:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][S:21][C:22]2[N:27]3[CH:28]=[CH:29][N:30]=[C:26]3[CH:25]=[CH:24][CH:23]=2)[C:12]1=[O:31])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]参加物
4
実験手順
To a solution of 2.24 g (4.87 mmol) of 5-decylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.55 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 2.38 g (98%, light yellow solid) of the desired product.