Hydrochloric Acid → 5-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

HRID 357050ノート

反応式

HRID 357050 の反応式
[CH:1](=[C:3]1[S:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH2:11][CH2:12][S:13][C:14]2[N:19]3[CH:20]=[CH:21][N:22]=[C:18]3[CH:17]=[CH:16][CH:15]=2)[C:4]1=[O:23])[CH3:2].[ClH:24]>CO>[ClH:24].[CH:1](=[C:3]1[S:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH2:11][CH2:12][S:13][C:14]2[N:19]3[CH:20]=[CH:21][N:22]=[C:18]3[CH:17]=[CH:16][CH:15]=2)[C:4]1=[O:23])[CH3:2]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 571831095-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione

生成物 1

HCID 867533445-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a solution of 0.48 g (1.38 mmol) of 5-ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.25 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 0.54 g (100%, yellow oily substance) of the desired product.

後処理

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

出典と根拠

ORDレコード
ord-fedb9ea52b21414c889418836b023284
出典データセット
uspto-grants-1998_11
特許番号
US05840732

反応ノート

読み込み中…