Water → HCID 54501552、化合物

HRID 357156ノート

反応式

HRID 357156 の反応式
C(O[CH:4]=[C:5]1[S:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])C.[Na].[CH2:13]([SH:15])[CH3:14].O>C(O)C>[CH2:13]([S:15][CH:4]=[C:5]1[S:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])[CH3:14]

参加物

5

反応物 3

HCID 962WaterHCID 45051917Sodium ethanethiolHCID 537875085-(Ethoxymethylene)thiazolidine-2,4-dione

生成物 1

HCID 54501552HCID 54501552、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To a suspension of 5.20 g of 5-(ethoxymethylene)thiazolidine-2,4-dione (1:1.71 mixture with thiazolidine-2,4-dione, about 13.9 mmol) in 50 ml of ethanol, 5.0 g (59 mmol) of ethanethiol sodium salt was added at room temperature, followed by stirring under heating conditions for 3 hours. After cooling, the reaction mixture was poured into water and adjusted to a pH level of about 2. The resulting precipitate was collected by filtration, washed with water and then with n-hexane/diethyl ether and dried to yield 1.38 g (52.0%, light yellow powder) of the desired product.

後処理

  1. additionwas added at room temperature
  2. temperatureAfter cooling
  3. filtrationThe resulting precipitate was collected by filtration
  4. washwashed with water
  5. dry with materialwith n-hexane/diethyl ether and dried

出典と根拠

ORDレコード
ord-f2c262a790024d35b3922934d789170b
出典データセット
uspto-grants-1998_11
特許番号
US05840732

反応ノート

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