5-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione → 5-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

HRID 357177ノート

反応式

HRID 357177 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[C:9]2[O:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[N:25]4[CH:26]=[CH:27][N:28]=[C:24]4[CH:23]=[CH:22][CH:21]=3)[C:10]2=[O:29])=[CH:4][CH:3]=1>CO.Cl>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[C:9]2[O:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[N:25]4[CH:26]=[CH:27][N:28]=[C:24]4[CH:23]=[CH:22][CH:21]=3)[C:10]2=[O:29])=[CH:6][CH:7]=1

参加物

4

反応物 1

HCID 543485705-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione

生成物 1

HCID 702053545-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 887Methanol溶媒

実験手順

To a solution of 0.301 g (0.70 mmol) of 5-(4-chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione in 10 ml of methanol, 0.10 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was crystallized by the addition of diethyl ether to yield 0.223 g (68.6%, light pink crystal) of the desired product.

後処理

  1. distillationAfter the solvent was distilled off
  2. customthe residue was crystallized by the addition of diethyl ether

出典と根拠

ORDレコード
ord-ddfa37448dd64177b4b7a815fc9c0367
出典データセット
uspto-grants-1998_11
特許番号
US05840732

反応ノート

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