関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methyl 6-aminohexanoate | HCID 1810164 | — |
| 溶媒 | Mesitylene | HCID 7947 | — |
| 生成物 | Caprolactam acetylene | HCID 86742408 | 260.4% |
反応手順
A solution of 37.1 g (0.256 mol) of methyl 6-aminocaproate in 723 g of mesitylene is stirred under reflux at 140° C./500 bar for 12 h. Evaporating off the mesitylene under reduced pressure leaves 46.4 g of a caprolactam-acetylene mixture which, according to HPLC, contains 58.2% of caprolactam, which corresponds to 27.0 g (0.239 mol) and a yield of 93.4%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04767857 |
|---|
| 出典データセット | uspto-grants-1988_08 |
|---|
| ORD ID | ord-955be329f2be48739f9d648bd81f7872 |
|---|
| 出典メモ | uspto-grants-1988_08 |
|---|
