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Hydrochloric Acid → Ampicillin Trihydrate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ampicillin | HCID 6249 | — |
| 生成物 | Ampicillin Trihydrate | HCID 23565 | — |
反応手順
The resultant crude protected ampicillin mixture is worked up by treating with a mixture of ice-water and concentrated HCl. After phase separation the aqueous phase is brought to pH 4.5. The title compound is obtained after filtration and washing with 90% aqueous acetone, followed by drying. Yield 66.34 g=89%. Purity 98.8%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05840885 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-1bf74494d5f2409fae1c1286e6520a37 |
| 出典メモ | uspto-grants-1998_11 |