1H-Pyrazole, 3,5-diphenyl- → 1-Methyl-3,5-diphenylpyrazole

HRID 357530

反応式

HRID 357530 の反応式
[C:1]1([C:7]2[CH:11]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S([O-])(O[CH3:22])(=O)=O>CO>[CH3:22][N:8]1[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:11][C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[N:9]1

参加物

4

反応物 2

HCID 708401H-Pyrazole, 3,5-diphenyl-HCID 4694097Methyl sulfate(1-)

生成物 1

HCID 1405171-Methyl-3,5-diphenylpyrazole収率 9,099%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

As in Example 2, a melt of 10 g (0.0455 mol) of 3,5-diphenylpyrazole and 0.051 g (0.000455 mol) of methyl sulfate was introduced and reacted over the course of 3 hours with 197.75 g (6.18 mol) of gaseous (vaporized at 160° C.) methanol. 9.7 g (86.7%) of 1-methyl-3,5-diphenylpyrazole were obtained, boiling point 190° C./3 mbar, with a content of 95.2% (GC).

出典と根拠

ORDレコード
ord-99e36d8a2d584b6698bbf3f0f957f199
出典データセット
uspto-grants-1998_11
特許番号
US05840913

関連ノート

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