関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2,3,5,6-Tetrafluorobenzotrichloride | HCID 15346297 | — |
| 反応物 | HCID 178418416 | HCID 178418416 | — |
| 触媒 | Iron chloride (FeCl3) | HCID 24380 | — |
| 溶媒 | Formic Acid | HCID 284 | — |
| 生成物 | 2,3,5,6-Tetrafluorobenzoyl Chloride | HCID 2734028 | — |
反応手順
268 g of 2,3,5,6-tetrafluorobenzotrichloride were placed in a 0.5 1 four necked flask. After addition of 5.4 g of iron(III) chloride, the mixture was heated to 60° C. with stirring. 46 g of formic acid were metered in over 6 hours at 60°-65° C. Vigorous gas development (carbon monoxide, hydrogen chloride) began immediately. The gas stream was fed to an absorption tower via a cooler. After addition was complete, the mixture was further stirred for two more hours at 60° C. The product was then distilled under reduced pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05840975 |
|---|
| 出典データセット | uspto-grants-1998_11 |
|---|
| ORD ID | ord-86d4e15bfa4a4cd9b2326a09bd9c5cb0 |
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| 出典メモ | uspto-grants-1998_11 |
|---|
