Water → HCID 178444469、化合物

HRID 35789ノート

反応式

HRID 35789 の反応式
[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][CH2:13][CH2:14][O:15][C:16]2[CH:23]=[CH:22][C:19]([CH:20]=[O:21])=[CH:18][CH:17]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].CC(C)=[O:26].OS(O)(=O)=O.O=[Cr](=O)=O.O>CC(C)=O>[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][CH2:13][CH2:14][O:15][C:16]2[CH:17]=[CH:18][C:19]([C:20]([OH:26])=[O:21])=[CH:22][CH:23]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

5

反応物 3

HCID 962WaterHCID 131709961Jones' reagentHCID 178444467HCID 178444467、化合物

生成物 1

HCID 178444469HCID 178444469、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A solution of 5 g of 4-[3-(trans-4-pentylcyclohexyl)-1-propyloxy]benzaldehyde in 100 ml of acetone was treated dropwise with 10 ml of Jones' reagent. The mixture was stirred at room temperature for 1 hour and then poured into 100 ml of water. The precipitate which thereby resulted was filtered off, washed portionwise with water and dried in a vacuum. The crude product was recrystallized from ethanol and gave 2.2 g of pure 4-[3-(trans-4-pentylcyclohexyl)-1-propyloxy]benzoic acid with m.p. (C-N) 204° C. and cl.p. (N-I) 215° C.

後処理

  1. customThe precipitate which thereby resulted
  2. filtrationwas filtered off
  3. washwashed portionwise with water
  4. customdried in a vacuum
  5. customThe crude product was recrystallized from ethanol

出典と根拠

ORDレコード
ord-2153413105e149348b781af770532b35
出典データセット
uspto-grants-1995_05
特許番号
US05411676

反応ノート

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