Sodium Bicarbonate → 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-

HRID 358295

反応式

HRID 358295 の反応式
O[C:2]1([CH3:11])[CH:6]([CH2:7][CH:8]=[CH2:9])[C:5](=[O:10])[CH:4]=[CH:3]1.C(=O)([O-])[OH:13].[Na+]>>[CH2:7]([C:6]1[C:5](=[O:10])[CH2:4][CH:3]([OH:13])[C:2]=1[CH3:11])[CH:8]=[CH2:9]

参加物

3

反応物 2

HCID 516892Sodium BicarbonateHCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

生成物 1

HCID 110832-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-収率 75%

実験手順

In 200 ml of a 5% aqueous sodium hydrogencarbonate solution, was dissolved 29 g of 4-hydroxy-4-methyl-5-allyl-2-cyclopentenone. The solution was heated with stirring under reflux for one hour. After having been allowed to cool, the reaction mixture was extracted three times with chloroform. The extract solution was dried over anhydrous magnesium sulfate and freed from the chloroform by distillation. The residue was distilled in vacuo to obtain 21.7 g (75% yield) of 2-allyl-3-methyl-4-hydroxy-2-cyclopentenone boiling at 155° C./1 mmHg.

後処理

  1. temperatureThe solution was heated
  2. temperatureunder reflux for one hour
  3. temperatureto cool
  4. extractionthe reaction mixture was extracted three times with chloroform
  5. dry with materialThe extract solution was dried over anhydrous magnesium sulfate
  6. distillationfreed from the chloroform by distillation
  7. distillationThe residue was distilled in vacuo

出典と根拠

ORDレコード
ord-cd46fe39913045f795d3913d5218cf2d
出典データセット
uspto-grants-1984_08
特許番号
US04465862

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