Sodium Bicarbonate → 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-
反応式
O[C:2]1([CH3:11])[CH:6]([CH2:7][CH:8]=[CH2:9])[C:5](=[O:10])[CH:4]=[CH:3]1.C(=O)([O-])[OH:13].[Na+]>>[CH2:7]([C:6]1[C:5](=[O:10])[CH2:4][CH:3]([OH:13])[C:2]=1[CH3:11])[CH:8]=[CH2:9]参加物
3
実験手順
In 200 ml of a 5% aqueous sodium hydrogencarbonate solution, was dissolved 29 g of 4-hydroxy-4-methyl-5-allyl-2-cyclopentenone. The solution was heated with stirring under reflux for one hour. After having been allowed to cool, the reaction mixture was extracted three times with chloroform. The extract solution was dried over anhydrous magnesium sulfate and freed from the chloroform by distillation. The residue was distilled in vacuo to obtain 21.7 g (75% yield) of 2-allyl-3-methyl-4-hydroxy-2-cyclopentenone boiling at 155° C./1 mmHg.
後処理
- temperatureThe solution was heated
- temperatureunder reflux for one hour
- temperatureto cool
- extractionthe reaction mixture was extracted three times with chloroform
- dry with materialThe extract solution was dried over anhydrous magnesium sulfate
- distillationfreed from the chloroform by distillation
- distillationThe residue was distilled in vacuo
出典と根拠
- ORDレコード
- ord-cd46fe39913045f795d3913d5218cf2d
- 出典データセット
- uspto-grants-1984_08
- 特許番号
- US04465862
反応ノート
読み込み中…