関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dodecane, 1-isocyanato- | HCID 77873 | — |
| 反応物 | Quinoline, 1,2,3,4-tetrahydro-2,2,4-trimethyl- | HCID 107292 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | N-n-Dodecylaminocarbonyl-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | HCID 12901826 | 66% |
反応手順
0.1 mole of 2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline is dissolved in 50 ml of ether and the solution is mixed with 0.1 mole of n-dodecyl isocyanate. A spatula tip of diazadicyclooctane is then added, the mixture is left to stand for 7 days at 20° to 25° C. and cooled at -70° C. and the precipitate which has separated out is filtered off. N-n-Dodecylaminocarbonyl-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline with a melting point of 48°-50° C. is obtained. Yield: 66% of theory.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04466964 |
|---|
| 出典データセット | uspto-grants-1984_08 |
|---|
| ORD ID | ord-7a959d971acf4df9b13af608de9f97a4 |
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| 出典メモ | uspto-grants-1984_08 |
|---|
