化工社化工社 化学情報印刷レポート · 研究参考用
Methyl Isocyanate → N,2-Dimethyl-2,3-dihydro-1H-indole-1-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl Isocyanate | HCID 12228 | — |
| 反応物 | 2-Methylindoline | HCID 23305 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N,2-Dimethyl-2,3-dihydro-1H-indole-1-carboxamide | HCID 12321965 | 89% |
反応手順
1 mole of 2-methylindoline is dissolved in 300 ml of toluene and 1 mole of methyl isocyanate is added, the temperature not rising above 25° C. The mixture is left to stand for 1 day and the resulting precipitate is then filtered off. N-Methylaminocarbonyl-2-methylindoline with a melting point of 158°-160° C. is obtained. Yield: 89% of theory.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04466964 |
| 出典データセット | uspto-grants-1984_08 |
| ORD ID | ord-301534f4b203478c9dc009a74deb5d9e |
| 出典メモ | uspto-grants-1984_08 |