4alpha-Phorbol → Phorbol ethyl acetate

HRID 358428

反応式

HRID 358428 の反応式
[CH3:1][C@H:2]1[C@:10]2([OH:24])[C@H:11]3[C@:16]([OH:22])([CH2:17][C:18]([CH2:20][OH:21])=[CH:19][C@H:9]2[C@@H:5]2[C:6]([CH3:8])([CH3:7])[C@:4]2([OH:25])[C@@H:3]1[OH:26])[C:14](=[O:15])[C:13]([CH3:23])=[CH:12]3.C[C@H]1[C@]2(O)[C@H]3[C@@](O)(CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]2(O)[C@@H]1O)[C:40](=[O:41])[C:39](C)=C3>>[CH3:1][C@H:2]1[C@:10]2([OH:24])[C@H:11]3[C@:16]([OH:22])([CH2:17][C:18]([CH2:20][OH:21])=[CH:19][C@H:9]2[C@@H:5]2[C:6]([CH3:7])([CH3:8])[C@:4]2([OH:25])[C@@H:3]1[OH:26])[C:14](=[O:15])[C:13]([CH3:23])=[CH:12]3.[C:40]([O:21][CH2:20][CH3:18])(=[O:41])[CH3:39]

参加物

3

反応物 2

HCID 1147084alpha-PhorbolHCID 442070Phorbol

生成物 1

HCID 70519647Phorbol ethyl acetate

実験手順

Characterization of phorbol and 4α-phorbol. White needles of phorbol-ethyl acetate solvate (8.9 mg; 0.34% w/w; m.p. 230° C.) were obtained after crystallization from ethyl acetate, which exhibited identical thin-layer chromatography and mass spectral characteristics to an authentic sample of the compound.

出典と根拠

ORDレコード
ord-94511e3504db41329b60b38806f822be
出典データセット
uspto-grants-1984_08
特許番号
US04468328

関連ノート

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