化工社化工社 化学情報印刷レポート · 研究参考用
6,6-Dibromopenicillanic acid → Penicillanic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6,6-Dibromopenicillanic acid | HCID 90376 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 触媒 | Calcium Palladium Carbonate | HCID 12000666 | — |
| 生成物 | Penicillanic Acid | HCID 6891 | — |
| 生成物 | 6,6-Dibromopenicillanic acid | HCID 90376 | — |
反応手順
Pratt, U.S. Pat. No. 4,180,506, describes catalytic hydrogenation of 6,6-dibromopenicillanic acid over Pd/C catalyst to produce a mixture of 6-alpha- and 6-beta-bromopenicillanic acid. Clayton, J. Chem. Soc. (C), pp. 2123-2127 (1969), describes the hydrogenation of methyl 6,6-dibromopenicillanate over Pd/CaCO3 to produce methyl 6-alpha-bromopenicillanate and methyl penicillanate; and hydrogenation of 6,6-dibromopenicillanic acid over the same catalyst to produce penicillanic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04468351 |
| 出典データセット | uspto-grants-1984_08 |
| ORD ID | ord-433695d9204e48309c42fc99dc140bbc |
| 出典メモ | uspto-grants-1984_08 |