Methyl (Z)-7-phthalimidohept-5-enoate → (Z)-7-Phthalimidohept-5-enoic Acid
反応式
[C:1]1(=[O:21])[N:5]([CH2:6]/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([O:14]C)=[O:13])[C:4](=[O:16])[C:3]2=[CH:17][CH:18]=[CH:19][CH:20]=[C:2]12>CC(C)=O.Cl.O>[C:4]1(=[O:16])[N:5]([CH2:6]/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[C:1](=[O:21])[C:2]2=[CH:20][CH:19]=[CH:18][CH:17]=[C:3]12参加物
5
実験手順
A solution of methyl (Z)-7-phthalimidohept-5-enoate (1.56 g) in acetone (30 ml), concentrated hydrochloric acid (15 ml) and water (15 ml) was refluxed for 2.5 hours. Water (180 ml) was added and the solution was cooled. The precipitate was collected by filtration to give the title compound (1.2 g). m.p. 86°-88° C.
後処理
- temperaturethe solution was cooled
- filtrationThe precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-2b262f54b69b4c24a4ef5f86f10f6fce
- 出典データセット
- uspto-grants-1991_03
- 特許番号
- US04997847
反応ノート
読み込み中…